The Nervous system (Read: Behave: The Biology of Humans at Our Best and Worst)
- Sensory nervous – carry input messages from sense organs to brain and spinal cord
- (Study Tip: senses to brain)
- Motor neurons – carry output impulses from brain and spinal cord to the body’s muscles and organs
- (Study Tip: motor as in running which requires muscle. Therefore, takes messages from brain to muscles through the spinal cord)
- Interneurons – perform connective or associative functions within the nervous system
- most in number
- (Study Tip: Inter =in-between)
- Glial cells do not send or receive nerve impulses but hold the neurons and their surroundings areas together.
- (Study Tip: G for Glial, G for gluing. Holding neurons together)
- The Nervous System is divided into two major parts
- Peripheral Nervous System – all neural structure that lie outside the brain and spinal cord
- Further divided into two parts
- Somatic nervous system
- Autonomic nervous system
- Somatic nervous system – transmits messages from brain & spinal cord to and from voluntary controlled muscles.
- Autonomic nervous system – Responsible for controlling body’s internal, involuntary (smooth) muscles and glands.
- Further divided into two categories:
- Sympathetic nervous system
- Parasympathetic nervous system
- Further divided into two categories:
- Sympathetic nervous system- works on the arousal function and acts as a total unit.
- Responsible for ‘fight or flight’ response.
- The response is seen with the following behaviour:
- Increased sweating,
- pupil dilation,
- heartbeat increase,
- breathing increases,
- lump digestion
- Parasympathetic division affects specific organ(s) at a time. In opposition to the sympathetic division it slows down body processes to maintain equilibrium.
- The responses are opposite to the ‘flight or fight response’.
- (Study Tip: Periphery meaning everything away from brain and spinal cord)
- (Study Tip: two parts, Somatic meaning body and related to voluntary body parts;
Autonomic meaning automatic, therefore, involuntary parts. Further subdivided into Sympathetic and parasympathetic) - (Study Tip: Sympathetic is sympathetic to body and responds to stimuli by fight or flight. Parasympathetic is opposite and slows everything down similar to a slight crude form called paralysis; Remembering anyone will bring the meaning of the other to mind)
- Body and Brain are in constant flux to attain Homeostasis i.e. state of internal balance
- The Central Nervous System – contains the brain and spinal cord.
- It connect most parts of the Peripheral Nervous System with the brain.
- Spinal cord – is 16 to 18 inch long and 1 inch in diameter.
- It is protected by the vertebrae
- Spinal reflexes are stimulus response sequences that can be triggered without the involvement of the brain. This reduces reaction time and helps in emergency situations.
- 31 pairs of spinal nerves
- Arranged from top to bottom:
- Cervical (8)
- Thoracic (12)
- Lumbar (5)
- Sacral (5)
- Coccygeal (1)
- (Study Tip: CT (as in ct scan)-VSCo (as in instagram camera)
- 3 meninges protect it as well (arranged innermost-outermost)
- Pia
- Arachorid
- Dura
- (Study Tip: PADding)
Structure of the Brain (HIND-MID-FORE)
- The Hindbrain – lowest and the primitive part of the brain;
- Consists of the areas of the brain stem and the cerebellum
- Brain stem – supports vital life functions. Consists of the medulla and pons.
- Medulla is responsible for:
- Heart rate and perspiration
- Crossover point for sensory and motor nerves from and to right and left sides of the brain
- Pons
- Above the medulla and is responsible for
- Carrying nerve impulses between the higher and lower levels of nervous system
- Sleep and respiration
- Above the medulla and is responsible for
- Cerebellum
- Looks like a mini brain
- Wrinkled cortex of gray matter and is responsible for
- coordinating muscular movement,
- learning and memory
- Alcohol consumption diminishes coordination
- Trivia: Cats have a highly functional cerebellum
- (Study Tip: Hind brain = MPC-bellum)
- The Midbrain
- Located above the hindbrain
- Consists of the reticular formation, tectum, the cerebral aqueduct, tegmentum, and the cerebral peduncles.
- Contains clusters of sensory and motor neurons
- Responsible for:
- Visual and auditory relay centres → forebrain
- eye movements
- Reticular formation
- Finger shaped, deep within forebrain
- Acts as a sentry, alerting higher centres and allowing or blocking incoming messages
- Responsible for: Consciousness, sleep and attention
- (Study Tip: mid brain has only reticular formation that important)
- The Forebrain
- The most advanced portion from an evolutionary standpoint
- Consists of the Cerebrum
- All parts such as Thalamus, Hypothalamus, Limbic System, Cerebral cortex, are located in the Cerebrum
- Cerebrum
- Wraps around the brain stem
- Two large hemispheres (left and right)
- Thalamus
- Located above the midbrain
- Part of the cerebral spheres
- Switchboard function: sends sensory nerve impulse to appropriate areas
- Visual, auditory and body senses (balance and equilibrium)
- Schizophrenia patients have an abnormally functioning thalamus that relays information to parts that do not need that information.
- Hypothalamus
- Located at the base of the brain,
- below Thalamus
- Responsible for:
- Motivation & emotion,
- temperature regulation,
- sleeping,
- eating,
- drinking and aggression
- Regulates endocrine and pituitary gland
- James Olds found that hypothalamus has pleasure areas where dopamine works and is responsible for rewards and punishments
- Located at the base of the brain,
- Limbic system
- Located deep within the cerebral hemisphere
- Responsible for:
- Satisfying urges that occur in the hypothalamus related to motivation and emotion
- Inbred in memory as well
- Two structures exist within the limbic system:
- Hippocampus
- Responsible for the formation and retrieval of memories
- Damage can lead to severe impairment of recent memories
- Responsible for the formation and retrieval of memories
- Amygdala
- Also known as the fear centre
- Organises motivation and emotional patterns related to aggression and fear
- Reward and punishment centres for motivation sectors of limbic system
- Hippocampus
- The Cerebral Cortex
- Made up of gray (unmylenated) cells forming the outermost layer of the brain
- 80% of brain tissue
- It has fissures that are divided into four lobes based on sensory and motor function
- The folds of wrinkled cortex looks like a canyon
- Some division made by the fissures don’t involve sensory or motor function and are known as Association cortex
- Responsible for mental processes of thought, memory and perception
- Frontal lobe (planning and execution)
- self-awareness, planning, initiative and responsibility and emotional experience
- Prefrontal cortex
- Located behind forehead,
- Responsible for:
- executive functioning,
- goal setting,
- judgement,
- impulse control
- Motor cortex
- Responsible for more than 600 voluntary muscles in body
- Located at the rear end of frontal lobe
- Body parts are arranged upside down in the motor cortex
- Information from legs is responded from the top portion of the frontal lobe
- Information from the upper portions of the body is responded by the lower portion of the frontal lobe
- Parietal (temperature)
- The sensory cortex
- Receives inputs for heat, touch and cold
- Balance and body movements
- Located behind motor cortex, and in front of parietal lobe
- Same upside down principle as motor cortex
- Receives inputs for heat, touch and cold
- The sensory cortex
- Temporal lobe is responsible for hearing
- Occipital is responsible for vision and sight
- Speech Comprehension and Production
- Werwick’s area
- located in the temporal lobe (left hemisphere)
- Responsible for speech comprehension (written or spoken)
- Broca’s area
- located in the frontal lobe (left hemisphere) close to motor cortex
- Responsible for facial muscle movement and speech production
- Damage to either leads to:
- Agnosia – inability to recognise familiar objects
- Aphasia – inability to comprehend and formulate language due to damage to specific brain regions
- Werwick’s area
- Association cortex
- mental function of perception, language and thought
- responsible for superior cognitive ability
- mental function of perception, language and thought
- (Study Tip: Everything else is here!)
- Brain lateralization
- Refers to the relatively greater localization of functions in each hemisphere
- Corpus callosum – connects left and right hemisphere
- Left hemisphere
- Responsible for speech production, comprehension, math/arithmetic ability, logical abilities, and positive emotions
- Right portions of the body are controlled by the LH
- Right hemisphere
- spatial relations, face recognition, and negative emotions
- Left portions of the body are controlled by the RH
- Refers to the relatively greater localization of functions in each hemisphere
- Brain lateralization
- (Study Tip: link one attribute of left brain and right brain to right and left handed people respectively. Consolidate that information)
- Split Brain – Roger Sperry
- When the corpus callosum is damaged and the hemisphere begin acting independently of one another
- Brain Plasticity also known as neuronal plasticity – ability of the neurons to change in structure and function.
- The production of new neurons in the nervous system is called Neurogenesis.
- Neural stem cells – uncommitted cells that can mature into any neuron of a degenerative area
- Split Brain – Roger Sperry
Neurotransmitters
- Acetylcholine (Ach) – muscle activity and memory. Reduced when suffering from Alzheimer’s disease
- Affects areas of Pons and basal forebrain
- (Study Tip: Ach as in ache, muscular ache, affects muscles)
- Norepinephrine
- excitatory and inhibitory, depending on site
- neural control of learning, memory, wakefulness and eating
- Depression, stress and panic disorders
- Norepinephrine
- (Study Tip: Neither/nor-ephinephrine – meaning both inhibitory and excitatory)
- Serotonin
- excitatory and inhibitory
- mood, sleep, eating, arousal
- Depression, sleeping-eating disorders, OCD
- secretion – Ralphe nuclei
- Serotonin
- (Study Tip: nin/non: meaning both inhibitory and excitatory)
- Dopamine
- excitatory,
- movement, emotional arousal
- Parkinson, depression and schizophrenia
- Dopamine
- (Study Tip: Dopa–Mine is exciting; excitatory)
- GABA
- inhibitory,
- motor system
- Huntington’s disease, loss of motor control and personality change
- GABA
- (Study Tip: GABAsounds boring. It’s definitely inhibitory)
- Endorphin
- Inhibitory
- inhibits pain transmission
- Insensitivity to pain, hypersensitivity, immune problems
- Endorphin
- (Study Tip: End-orphine is inhibitory)
- Neuromodulators are messengers released from neurons in the central or peripheral nervous system to affect a group of neurons
- They have a more generalized effect on synaptic transmission
- Neuromodulators are messengers released from neurons in the central or peripheral nervous system to affect a group of neurons
Behavioural genetics and environment
- Behaviour genetics – study how genetics and environment factors influence psychological characteristics
- Degree of similarity of responses of genetically similar people gives an indication of the impact of genetics
- Heritability
- Heritability statistic estimates the extent to which the difference in specific phenotype within a group of people can be attributed to their differing genes.
- Genetic basis of behaviour
- Genotype – the specific genetic makeup of an individual
- compared to a computer software
- Genes present from birth
- May or not may not manifest
- dependent upon other genes which hinder or help this gene activate
- Phenotype – are the observable characteristics of the individual.
- The genes that are present and are expressed,
- Difference between genotype and phenotype is that the genotype has all the genes but not necessary that all will be expressed
- Genotype – the specific genetic makeup of an individual
- Major contributor of gene understanding
- Gregor Mendel
- Organic factors of genes affect characteristics.
- Nucleus of all cells constituted by chromosomes
- 22 identical pairs in humans called autosomes
- Sex cells are called allosomes as the gene is different in shape, size and length compared to other chromosomes
- A chromosome is a double stranded, tightly coiled molecule of deoxyribonucleic acid (DNA).
- All information of heredity are in four chemical bases:
- Adenine
- Cytosine
- Thymine
- Guanine
- Nucleus of all cells constituted by chromosomes
- (Study Tip: ACT-G)
- Alleles are alternative characteristics that are developed due to alternative genes/mutation
- Dominant genes will display characteristics
- Recessive genes will not display characteristics unless two similar recessive genes are combined.
- Polygenic transmissions occurs when many genes contribute to make one single dominant trait
- Experience shapes behaviour in two ways:
- Fixed action pattern
- an unlearned automatic response triggered by a particular stimulus
- Species adaptation
- learning is not transferred by genes but through natural selection genetically based characteristics that enhance the ability of a species to adapt is transferred
- Fixed action pattern
- Two types of research studies to test genetics and heritability of behaviours
- Family studies – Degree of similarity of behaviour of genetically similar relatives in specific traits to the person in question
- Adoption studies – Degree of similarity of behaviour of adopted children with genetically similar (biological) parents and adoptive parents
Brain and other concepts
- Intelligence
- Identical twins reared together
- correlation is high
- Identical twins reared apart
- correlation nearly as high
- Fraternal twins
- IQ of adopted children correlate similarly with both their biological parents and adoptive parents
- (no single gene for intelligence)
- Genetics/Heredity account for 50-70% change in intelligence
- Siblings reared together have a high correlation in their IQ
- Correlation of .32 between unrelated adopted children living together
- Difference of home environment is more important in lower socio-economic conditions
- Evidence: children in impoverished homes moving to better homes show increase in IQ by 10-12 points.
- Identical twins reared together
- Schizophrenia: Studied by Seymour Ketty
- Schizophrenia (12% similar genes)
- Twin studies
- compared trait similarities in identical and fraternal monozygotic twins
- Trait similarity a.k.a. high concordance rates
- High correlation in case of schizophrenia with family members
- Personality (Reading: Personality Psychology)
- Genetic differences account for .50 correlation between similar genotype individuals
- Important finding was that family environment played very limited role in determining personality, except when extremes of neglect and abuse occur.
- Similar results for twin and adoptive studies.
- Gene-environment interaction
- The environment cannot affect the genotype but only its expression and phenotype
- Reaction range
- Is the measure of how much the environment can affect genes
- Intellectual growth depends on both factors i.e. genes and environment
- Evocative influence
- A child’s genetically influenced behaviour may evolve certain responses from others
- Introvert/extrovert children
- Gene experimentation
- Knockout procedure
- A particular function of a gene is removed
- Knockout procedure
- All vertebrates have a bilaterally symmetrical body plan
- Anatomy of dissected in the following manner
- Proximal – closer to the trunk
- Distal – away from the trunk
- Lateral – away from midline
- Medial – closer to midline
- Anterior – front side
- Posterior – back side
- Endocrine system – consists of numerous hormone secreting glands distributed throughout the body.
- Messages to the body are distributed through hormones secreted via glands
- Hormones are chemical messengers secreted into the bloodstream
- Brain decides which impulse to send, between endocrine and nerve impulse, or both
- Hormones affect us from prenatal stage
- They affect aggressiveness, sex differences, immune system and so on
- Immune system
- foreign substance (antigens) are removed by antibodies
- Stress, depression, negative thinking reduce immune functioning
- Candence Pest suggested that the nervous, endocrine and immune system are related
- Glands are organs in the body that secrete chemicals
- Endocrine glands
- secrete enzymes into the ‘bloodstream’ called hormones, usually from sympathetic division of ANS
- Hormones affect behaviour and emotions through organs like heart, pancreas, sex organs.
- Pituitary gland also known as Master gland
- controls all other glands
- located below hypothalamus
- influences events related to pregnancy – production of milk, onset of labos, salt and water
- Endocrine glands
- Growth hormone
- regulates and controls increase in size of body parts
- Pineal gland
- secretes melatonin
- located nearer to the back of brain
- regulates sleep wake cycle (Read: Why We Sleep)
- Thyroid gland
- secretes thyroxin
- located inside neck
- regulates metabolism
- Pancreas
- secretes insulin and glucagon
- low insulin = diabetes
- high insulin = hypoglycaemia
- located in torso
- regulates blood sugar
- secretes insulin and glucagon
- Gonads
- secretes androgens, oestrogen, progesterone, and testosterone
- located in the ovaries (females) and testes (males)
- regulates sexual behaviour along with the brain
- Adrenal gland
- on top of each kidney
- Two types:
- Adrenal medulla
- secretes epinephrine and norepinephrine
- regulates stress and sympathetic arousal
- Adrenal cortex
- secretes 30 different hormones called corticoids (steroids)
- regulates salt intake, stress reaction, sex hormones
- Cortisol
- released under stress
- releases glucose into bloodstream
- provides energy to body and brain by burning fatty acids from fat cells
- Adrenal medulla
Suggested Reading(s):
Behave: The Biology of Humans at Our Best and Worst
Sapiens: A Brief History of Humankind
Who We Are and How We Got Here: Ancient DNA and the new science of the human past
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